Joseph S. Solomkin, M.D.

Joseph S. Solomkin, M.D.

Executive Director, ISIS Board of Directors

Dr. Solomkin is a surgeon, professor, and world traveler. A primary focus through his many years of surgical practice has been surgical site infections and ways to minimize their occurrence and effects. He has become a global expert in this field and is now spending much of his time and resources traveling the world presenting lectures.

With his unique skills and experience and vast travels, he is acutely aware of the health-care situation in many developing countries and is extremely passionate about improving the global surgical care situation. Dr. Solomkin has organized ISIS to be the conduit for these improvements. He currently serves as the president of our board and primary fundraiser.

After completing his undergraduate degree at Harvard University in 1966, Dr. Solomkin pursued his medical education at the Albert Einstein College of Medicine in New York, graduating in 1970. Following his internship at that facility, he volunteered for airborne and special forces training as a medical officer in the U.S. Army. He served with various special forces groups in Okinawa, Vietnam and Thailand (1971-3). He was awarded two bronze stars during his tour in Vietnam.

Dr. Solomkin then returned to his surgical training at the University of Minnesota Hospitals (1973-9), and then undertook an extramural NIH fellowship in surgical infections there. After a subsequent year on that faculty, he joined the Department of Surgery at the University of Cincinnati, College of Medicine as a general surgeon, sub-specializing in burns and trauma in 1981.

In addition to his general surgical practice, Dr. Solomkin has worked as a critical care physician in the Surgical Intensive Care Unit (SICU) at the University of Cincinnati Hospitals since 1981. He received certification of added competence in surgical critical care from the American Board of Surgery (1991-present).

Among his other clinical and research responsibilities, he was program director for an NIH T32 post-doctoral training program (since 1993), and had an active laboratory effort funded by the NIH and by the Shriners Burns Institute studying the effect of trauma and sepsis on white blood cell function.

Dr. Solomkin has been involved as the PI of several phase II and III trials of antibiotics in surgical infections, particularly regarding intra-abdominal and soft tissue infections. He is recognized as an international authority on these infections.

Since becoming Professor Emeritus in 2009, he has continued clinical work at the University of Cincinnati Medical Center and works in the Antimicrobial Stewardship Program and the Surgical Care Improvement Project. He is involved in several guideline projects, including work with the CDC, FDA, and WHO.

 

 

CURRENT POSITION Professor of Surgery Emeritus

Department of Surgery

University of Cincinnati College of Medicine

 

Director, Surgical Antimicrobial Stewardship Program

University of Cincinnati Hospital

 

College: Harvard College B.A. 1962-1966

Cambridge, Massachusetts

 

Medical School: Albert Einstein M.D. 1966-1970

College of Medicine

Bronx, New York

 

Internship: Bronx Municipal 1970-1971

Hospital CenterAlbert Einstein

College of Medicine (Internal Medicine)

Bronx, New York

 

MILITARY SERVICE

 

Position: Captain, U.S. Army 1971-1973

Medical Corps

 

Service: Okinawa, Vietnam, Thailand

 

Decorations: Parachutist Badge

Bronze Star (x2)

Combat Medical Badge

 

RESIDENCY Jr. Resident (Surgery) 1973-1975

University of Minnesota

Minneapolis, Minnesota

 

Associate and Chief                1977-1979

Resident (Surgery)

University of Minnesota

Minneapolis, Minnesota

 

FOREIGN SERVICE Surgical Officer                   1975-1976

Piper Memorial Hospital

Kapanga, Zaire

 

FELLOWSHIP Surgical Infectious Diseases       1979-1980

University of Minnesota

Minneapolis, Minnesota

(NIH Fellowship F32 AMO5696)

Instructor                         1980-1981

Department of Surgery

St. PaulRamsey Medical Center

St. Paul, Minnesota

(University of Minnesota)

 

Assistant Professor 1981-1988

Department of Surgery

University of Cincinnati College of Medicine

 

Associate Professor 1988-1994

Department of Surgery

University of Cincinnati College of Medicine

 

Professor            1994-2009

Department of Surgery

University of Cincinnati College of Medicine

Director of Research, Division of Trauma/Critical Care

 

 

LICENSURE Ohio (# 35-04-6805)

 

BOARD CERTIFICATION American Board of Surgery (Surgical Critical Care)

 

 

PROFESSIONAL ORGANIZATIONS

 

Society of University Surgeons

Surgical Infection Society of North America1

                         Association for Academic Surgery

                          American College of Surgeons

Central Surgical Association

American Burn Association

Cincinnati Surgical Society

Society for Critical Care Medicine

American Society for Microbiology

Infectious Diseases Society of America

Society for Healthcare Epidemiology of America

Society for Leukocyte Biology

American Association of Immunologists

Peer Reviewed (Medline)

 

  1. Yokoe M, Takada T, Strasberg SM, et al. New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo guidelines. Journal of hepato-biliary-pancreatic sciences 2012;19:578-85.
  2. Solomkin JS, Gomi H. Reply to Beheshti et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012.
  3. Kiriyama S, Takada T, Strasberg SM, et al. New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo guidelines. Journal of hepato-biliary-pancreatic sciences 2012;19:548-56.
  4. Crawford, T, Rodvold KA,Solomkin JS. Vancomycin for surgical prophylaxis? Clin Infect Dis. 2012 May;54(10):1474-9.
  5. Goldstein EJ, Solomkin JS, Citron DM, Alder JD. Clinical Efficacy and Correlation of Clinical Outcomes With In Vitro Susceptibility for Anaerobic Bacteria in Patients With Complicated Intra-abdominal Infections Treated With Moxifloxacin. Clin Infect Dis. 2011 Dec;53(11):1074-80.
  6. Martin GJ, Dunne JR, Cho JM, Solomkin JS. Prevention of infections associated with combat-related thoracic and abdominal cavity injuries. J Trauma 2011 Aug; 71(2 Suppl 2):S270-S281.
  7. Hospenthal DR, Murray CK, Andersen RC, et al. Guidelines for the prevention of infections associated with combat-related injuries: 2011 update: endorsed by the Infectious Diseases Society of America and the Surgical Infection Society. J Trauma 2011 Aug; 71(2 Suppl 2):S210-S234.
  8. Hospenthal DR, Murray CK, Andersen RC, et al. Executive summary: Guidelines for the prevention of infections associated with combat-related injuries: 2011 update: endorsed by the Infectious Diseases Society of America and the Surgical Infection Society. J Trauma 2011 Aug; 71(2 Suppl 2):S202-S209.
  9. File TM, Jr., Solomkin JS, Cosgrove SE. Strategies for improving antimicrobial use and the role of antimicrobial stewardship programs. Clin Infect Dis 2011 Aug; 53 Suppl 1:S15-S22.
  10. Alexander JW, Solomkin JS, Edwards MJ. Updated recommendations for control of
  11. surgical site infections. Ann Surg. 2011 Jun;253(6):1082-93.
  12. Chaudhury P, Marshall JC, Solomkin JS. CAGS and ACS evidence based reviews in surgery. 35: Efficacy and safety of low-dose hydrocortisone therapy in the treatment of septic shock. Can J Surg 2010 Dec ; 53(6):415-7.
  13. Solomkin JS. Evaluating evidence and grading recommendations: the SIS/IDSA guidelines for the treatment of complicated intra-abdominal infections. Surg Infect (Larchmt ) 2010 Jun; 11(3):269-74.
  14. McClaine RJ, Husted TL, Hebbeler-Clark RS, Solomkin JS. Meta-analysis of trials evaluating parenteral antimicrobial therapy for skin and soft tissue infections. Clin Infect Dis 2010 Apr 15; 50(8):1120-6.
  15. Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect (Larchmt ) 2010 Feb; 11(1):79-109.
  16. Kasten KR, Goetzman HS, Reid MR, et al. Divergent adaptive and innate immunological responses are observed in humans following blunt trauma. BMC Immunol 2010; 11:4.
  17. Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis 2010 Jan 15; 50(2):133-64.
  18. Guerrero DM, Perez F, Conger NG, et al. Acinetobacter baumannii-associated skin and soft tissue infections: recognizing a broadening spectrum of disease. Surg Infect (Larchmt ) 2010 Feb; 11(1):49-57.
  19. Solomkin J, Zhao YP, Ma EL, Chen MJ, Hampel B. Moxifloxacin is non-inferior to combination therapy with ceftriaxone plus metronidazole in patients with community-origin complicated intra-abdominal infections. Int J Antimicrob Agents 2009 Nov; 34(5):439-45.
  20. Solomkin JS, Mazuski J. Intra-abdominal sepsis: newer interventional and antimicrobial therapies. Infect Dis Clin North Am 2009 Sep; 23(3):593-608.
  21. Rangel EL, Butler KL, Johannigman JA, Tsuei BJ, Solomkin JS. Risk factors for relapse of ventilator-associated pneumonia in trauma patients. J Trauma 2009 Jul; 67(1):91-5.
  22. Zingarelli B, Hake PW, O’Connor M, et al. Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma. Crit Care Med 2009 Jun; 37(6):1978-87.
  23. Mazuski JE, Solomkin JS. Intra-abdominal infections. Surg Clin North Am 2009 Apr; 89(2):421-37.
  24. Kollef MH, Napolitano LM, Solomkin JS, et al. Health care-associated infection (HAI): a critical appraisal of the emerging threat-proceedings of the HAI Summit. Clin Infect Dis 2008 Oct 1; 47 Suppl 2:S55-S99.
  25. Wunderink RG, Mendelson MH, Somero MS, et al. Early microbiological response to linezolid vs vancomycin in ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus. Chest 2008 Dec; 134(6):1200-7.
  26. Murray CK, Hsu JR, Solomkin JS, et al. Prevention and management of infections associated with combat-related extremity injuries. J Trauma 2008 Mar; 64(3 Suppl):S239-S251.
  27. Hospenthal DR, Murray CK, Andersen RC, et al. Guidelines for the prevention of infection after combat-related injuries. J Trauma  2008 Mar; 64(3 Suppl):S211-S220.
  28. Noel GJ, Strauss RS, Amsler K, Heep M, Pypstra R, Solomkin JS. Results of a double-blind, randomized trial of ceftobiprole treatment of complicated skin and skin structure infections caused by gram-positive bacteria. Antimicrob Agents Chemother 2008 Jan; 52(1):37-44.
  29. Solomkin JS, Robinson CT, Cave CM, Ehmer B, Lentsch AB. Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and prime human neutrophils for enhanced adherence-dependent oxidant production. Shock 2007 Sep; 28(3):334-8.
  30. Namias N, Solomkin JS, Jensen EH, Tomassini JE, Abramson MA. Randomized, multicenter, double-blind study of efficacy, safety, and tolerability of intravenous ertapenem versus piperacillin/tazobactam in treatment of complicated intra-abdominal infections in hospitalized adults. Surg Infect (Larchmt ) 2007 Feb; 8(1):15-28.
  31. Yoshida M, Takada T, Kawarada Y, et al. Antimicrobial therapy for acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 2007; 14(1):83-90.
  32. Hirota M, Takada T, Kawarada Y, et al. Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 2007; 14(1):78-82.
  33. Tanaka A, Takada T, Kawarada Y, et al. Antimicrobial therapy for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 2007; 14(1):59-67.
  34. Anaissie EJ, Segal BH, Graybill JR, et al. Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt. Clin Infect Dis 2006 Oct 15; 43(8):1031-9.
  35. Solomkin JS, Robinson CT, Cave CM, et al. Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space. Shock 2006 May; 25(5):440-5.
  36. Gearhart M, Martin J, Rudich S, et al. Consequences of vancomycin-resistant Enterococcus in liver transplant recipients: a matched control study. Clin Transplant 2005 Dec; 19(6):711-6.
  37. Okaya T, Blanchard J, Schuster R, et al. Age-dependent responses to hepatic ischemia/reperfusion injury. Shock 2005 Nov; 24(5):421-7.
  38. Solomkin JS. Cost-effectiveness issues in ventilator-associated pneumonia. Respir Care 2005 Jul; 50(7):956-63.
  39. Williams MA, Cave CM, Quaid G, et al. Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production. Shock 2005 Apr; 23(4):371-6.
  40. Solomkin JS. Ventilator-associated pulmonary infection: the germ theory of disease remains viable. Microbes Infect 2005 Feb; 7(2):279-91.
  41. Cuschieri J, Umanskiy K, Solomkin J. PKC-zeta is essential for endotoxin-induced macrophage activation. J Surg Res 2004 Sep; 121(1):76-83.
  42. Solomkin J, Teppler H, Graham DR, et al. Treatment of polymicrobial infections: post hoc analysis of three trials comparing ertapenem and piperacillin-tazobactam. J Antimicrob Chemother 2004 Jun; 53 Suppl 2:ii51-ii57.
  43. Solomkin JS, Bjornson HS, Cainzos M, et al. A consensus statement on empiric therapy for suspected gram-positive infections in surgical patients. Am J Surg 2004 Jan; 187(1):134-45.
  44. Barboza E, Solomkin J, Goldstein EJ, et al. [New Beta-lactam agent in the treatment of intra-abdominal sepsis: double blind and randomized stage III study of ertapenem versus piperacillin/tazobactam]. Rev Gastroenterol Peru 2003 Jul; 23(3):192-8.
  45. Solomkin JS, Mazuski JE, Baron EJ, et al. Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis 2003 Oct 15; 37(8):997-1005.
  46. Solomkin JS, Umanskiy K. Intraabdominal sepsis: newer interventional and antimicrobial therapies for infected necrotizing pancreatitis. Curr Opin Crit Care 2003 Oct; 9(5):424-7.
  47. Umanskiy K, Robinson C, Cave C, et al. NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation. Surgery 2003 Aug; 134(2):378-83.
  48. Wilson SE, Solomkin JS, Le V, Cammarata SK, Bruss JB. A severity score for complicated skin and soft tissue infections derived from phase III studies of linezolid. Am J Surg 2003 Apr; 185(4):369-75.
  49. Solomkin JS, Yellin AE, Rotstein OD, et al. Ertapenem versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections: results of a double-blind, randomized comparative phase III trial. Ann Surg 2003 Feb; 237(2):235-45.
  50. Solomkin JS. Molecular mechanisms of slime production: a transferable operon explains how a saprophyte finds a home. Crit Care Med 2002 Dec; 30(12):2776.
  51. Quaid G, Cave C, Williams MA, Hennigan RF, Bokoch G, Solomkin JS. Mechanisms of human neutrophil oxidant production after severe injury. Surgery 2001 Oct; 130(4):669-75.
  52. Quaid G, Williams M, Cave C, Solomkin J. CXCR2 regulation of tumor necrosis factor-alpha adherence-dependent peroxide production is significantly diminished after severe injury in human neutrophils. J Trauma 2001 Sep; 51(3):446-51.
  53. Bauhofer A, Lorenz W, Stinner B, et al. Granulocyte-colony stimulating factor in the prevention of postoperative infectious complications and sub-optimal recovery from operation in patients with colorectal cancer and increased preoperative risk (ASA 3 and 4). Protocol for a controlled clinical trial developed by consensus of an international study group. Part two: design of the study. Inflamm Res 2001 Apr; 50(4):187-205.
  54. Lorenz W, Stinner B, Bauhofer A, et al. Granulocyte-colony stimulating factor in the prevention of postoperative infectious complications and sub-optimal recovery from operation in patients with colorectal cancer and increased preoperative risk (ASA 3 and 4). Protocol of a controlled clinical trial developed by consensus of an international study group. Part one: rationale and hypothesis. Inflamm Res 2001 Mar; 50(3):115-22.
  55. Solomkin JS. Antibiotic resistance in postoperative infections. Crit Care Med 2001 Apr; 29(4 Suppl):N97-N99.
  56. Solomkin JS. Focus on “Essential role for IL-6 in postresuscitation inflammation in hemorrhagic shock”. Am J Physiol Cell Physiol 2001 Feb; 280(2):C237-C238.
  57. Solomkin JS, Wilson SE, Christou NV, et al. Results of a clinical trial of clinafloxacin versus imipenem/cilastatin for intraabdominal infections. Ann Surg 2001 Jan; 233(1):79-87.
  58. Solomkin JS. Microbiology and antibiotic treatment–discussion forum on a study protocol on adjuvant treatment of mediastinitis with immunoglobulins (Pentaglobin) after cardiac surgery (ATMI). Eur J Surg Suppl 1999;(584):43-4.
  59. Walters DJ, Solomkin JS, Paladino JA. Cost effectiveness of ciprofloxacin plus metronidazole versus imipenem-cilastatin in the treatment of intra-abdominal infections. Pharmacoeconomics 1999 Nov; 16(5 Pt 2):551-61.
  60. Quaid GA, Cave C, Robinson C, Williams MA, Solomkin JS. Preferential loss of CXCR-2 receptor expression and function in patients who have undergone trauma. Arch Surg 1999 Dec; 134(12):1367-71.
  61. Williams MA, Cave CM, Quaid G, Solomkin JS. Chemokine regulation of neutrophil function in surgical inflammation. Arch Surg 1999 Dec; 134(12):1360-6.
  62. Jawa RS, Quaid GA, Williams MA, et al. Tumor necrosis factor alpha regulates CXC chemokine receptor expression and function. Shock 1999 Jun; 11(6):385-90.
  63. Lorenz W, Troidl H, Solomkin JS, et al. Second step: testing-outcome measurements. World J Surg 1999 Aug; 23(8):768-80.
  64. Williams MA, Solomkin JS. Integrin-mediated signaling in human neutrophil functioning. J Leukoc Biol 1999 Jun; 65(6):725-36.
  65. Joshi M, Bernstein J, Solomkin J, Wester BA, Kuye O. Piperacillin/tazobactam plus tobramycin versus ceftazidime plus tobramycin for the treatment of patients with nosocomial lower respiratory tract infection. Piperacillin/tazobactam Nosocomial Pneumonia Study Group. J Antimicrob Chemother 1999 Mar; 43(3):389-97.
  66. Bohnen JM, Marshall JC, Fry DE, Johnson SB, Solomkin JS. Clinical and scientific importance of source control in abdominal infections: summary of a symposium. Can J Surg 1999 Apr; 42(2):122-6.
  67. Solomkin JS, Dellinger EP, Bohnen JM, Rostein OD. The role of oral antimicrobials for the management of intra-abdominal infections. New Horiz 1998 May; 6(2 Suppl):S46-S52.
  68. Vincent JL, Anaissie E, Bruining H, et al. Epidemiology, diagnosis and treatment of systemic Candida infection in surgical patients under intensive care. Intensive Care Med 1998 Mar; 24(3):206-16.
  69. Heard SO, Fink MP, Gamelli RL, et al. Effect of prophylactic administration of recombinant human granulocyte colony-stimulating factor (filgrastim) on the frequency of nosocomial infections in patients with acute traumatic brain injury or cerebral hemorrhage. The Filgrastim Study Group. Crit Care Med 1998 Apr; 26(4):748-54.
  70. Barie PS, Vogel SB, Dellinger EP, et al. A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group. Arch Surg 1997 Dec; 132(12):1294-302.
  71. Edwards JE, Jr., Bodey GP, Bowden RA, et al. International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections. Clin Infect Dis 1997 Jul; 25(1):43-59.
  72. Solomkin JS. Timing of treatment for nonneutropenic patients colonized with Candida. Am J Surg 1996 Dec; 172(6A):44S-8S.
  73. Solomkin JS. Antimicrobial resistance: an overview. New Horiz 1996 Aug; 4(3):319-20.
  74. Solomkin JS, Reinhart HH, Dellinger EP, et al. Results of a randomized trial comparing sequential intravenous/oral treatment with ciprofloxacin plus metronidazole to imipenem/cilastatin for intra-abdominal infections. The Intra-Abdominal Infection Study Group. Ann Surg 1996 Mar ; 223(3):303-15.
  75. Burnett RJ, Lyden CA, Tindal CJ, Cave CM, Marra MN, Solomkin JS. Mononuclear cell line THP-1 internalizes bactericidal/permeability-increasing protein by a non-receptor-mediated mechanism consistent with pinocytosis. Arch Surg 1996 Feb; 131(2):200-5.
  76. Solomkin JS. Duration of antibiotic treatment in surgical infections of the abdomen. The future: randomised prospective studies. Eur J Surg Suppl 1996;(576):33-5.
  77. Burnett RJ, Haverstock DC, Dellinger EP, et al. Definition of the role of enterococcus in intraabdominal infection: analysis of a prospective randomized trial. Surgery 1995 Oct; 118(4):716-21.
  78. Gianotti L, Solomkin JS, Munda R, Alexander JW. Failure of local and systemic bacterial clearance in rats with acute pancreatitis. Pancreas 1995 Jan; 10(1):78-84.
  79. Aloia T, Solomkin J, Fink AS, et al. Candida in pancreatic infection: a clinical experience. Am Surg 1994 Oct; 60(10):793-6.
  80. Solomkin JS, Miyagawa CI. Principles of antibiotic therapy. Surg Clin North Am 1994 Jun; 74(3):497-517.
  81. Solomkin JS, Tindal CJ, Cave CM, Zemlan F. Regulation of TNF-alpha receptor expression on human neutrophils by various cell activating factors. J Surg Res 1994 Mar; 56(3):261-6.
  82. Solomkin JS, Bass RC, Bjornson HS, Tindal CJ, Babcock GF. Alterations of neutrophil responses to tumor necrosis factor alpha and interleukin-8 following human endotoxemia. Infect Immun 1994 Mar; 62(3):943-7.
  83. Solomkin JS. Very large-scale, randomized, clinical trials in sepsis and septic shock. Crit Care Med 1994 Jan; 22(1):1-2.
  84. de LG, Elixhauser A, Luce BR, et al. Cost analysis of imipenem-cilastatin versus clindamycin with tobramycin in the treatment of acute intra-abdominal infection. Pharmacoeconomics 1993 Sep; 4(3):203-14.
  85. Solomkin JS. Pathogenesis and management of Candida infection syndromes in non-neutropenic patients. New Horiz 1993 May; 1(2):202-13.
  86. Page CP, Bohnen JM, Fletcher JR, McManus AT, Solomkin JS, Wittmann DH. Antimicrobial prophylaxis for surgical wounds. Guidelines for clinical care. Arch Surg 1993 Jan; 128(1):79-88.
  87. Sweet RL, Bartlett JG, Hemsell DL, Solomkin JS, Tally F. Evaluation of new anti-infective drugs for the treatment of acute pelvic inflammatory disease. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis 1992 Nov; 15 Suppl 1:S53-S61.
  88. Hemsell DL, Solomkin JS, Sweet R, Tally F, Bartlett JG. Evaluation of new anti-infective drugs for the treatment of acute pelvic infections in hospitalized women. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis 1992 Nov; 15 Suppl 1:S43-S52.
  89. Solomkin JS, Hemsell DL, Sweet R, Tally F, Bartlett J. Evaluation of new anti-infective drugs for the treatment of intraabdominal infections. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis 1992 Nov; 15 Suppl 1:S33-S42.
  90. Bohnen JM, Solomkin JS, Dellinger EP, Bjornson HS, Page CP. Guidelines for clinical care: anti-infective agents for intra-abdominal infection. A Surgical Infection Society policy statement. Arch Surg 1992 Jan; 127(1):83-9.
  91. Solomkin JS. Neutrophil disorders in burn injury: complement, cytokines, and organ injury. J Trauma 1990 Dec; 30(12 Suppl):S80-S85.
  92. Solomkin JS, Dellinger EP, Christou NV, Busuttil RW. Results of a multicenter trial comparing imipenem/cilastatin to tobramycin/clindamycin for intra-abdominal infections. Ann Surg 1990 Nov; 212(5):581-91.
  93. Tennenberg SD, Clardy CW, Bailey WW, Solomkin JS. Complement activation and lung permeability during cardiopulmonary bypass. Ann Thorac Surg 1990 Oct; 50(4):597-601.
  94. Nystrom PO, Bax R, Dellinger EP, et al. Proposed definitions for diagnosis, severity scoring, stratification, and outcome for trials on intraabdominal infection. Joint Working Party of SIS North America and Europe. World J Surg 1990 Mar; 14(2):148-58.
  95. Tennenberg SD, Solomkin JS. Activation of neutrophils by cachectin/tumor necrosis factor: priming of N-formyl-methionyl-leucyl-phenylalanine-induced oxidative responsiveness via receptor mobilization without degranulation. J Leukoc Biol 1990 Mar; 47(3):217-23.
  96. Ogle CK, Johnson C, Guo XL, Ogle JD, Solomkin JS, Alexander JW. Production and release of C3 by cultured monocytes/macrophages isolated from burned, trauma, and septic patients. J Trauma 1989 Feb; 29(2):189-94.
  97. Tennenberg SD, Zemlan FP, Solomkin JS. Characterization of N-formyl-methionyl-leucyl-phenylalanine receptors on human neutrophils. Effects of isolation and temperature on receptor expression and functional activity. J Immunol 1988 Dec 1; 141(11):3937-44.
  98. Solomkin JS. Use of new beta-lactam antibiotics for surgical infections. Surg Clin North Am 1988 Feb; 68(1):1-24.
  99. Tennenberg SD, Solomkin JS. Neutrophil activation in sepsis. The relationship between fmet-leu-phe receptor mobilization and oxidative activity. Arch Surg 1988 Feb; 123(2):171-5.
  100. Tennenberg SD, Solomkin JS. Surface receptor mobilization in complement-mediated neutrophil activation: characterization and effects of methylprednisolone. J Surg Res 1987 Aug; 43(2):143-8.
  101. Tennenberg SD, Solomkin JS. Increased expression of neutrophil chemoattractant receptors in sepsis: correlation with functional activation. Curr Surg 1987 Jul; 44(4):313-5.
  102. Waymack JP, Jenkins M, Warden GD, et al. A prospective study of thymopentin in severely burned patients. Surg Gynecol Obstet 1987 May; 164(5):423-30.
  103. Tennenberg SD, Jacobs MP, Solomkin JS, Ehlers NA, Hurst JM. Increased pulmonary alveolar-capillary permeability in patients at risk for adult respiratory distress syndrome. Crit Care Med 1987 Apr; 15(4):289-93.
  104. Antrum RM, Solomkin JS. A review of antibiotic prophylaxis for open fractures. Orthop Rev 1987 Apr; 16(4):246-54.
  105. Solomkin JS, Dellinger EP, Christou NV, Mason AD, Jr. Design and conduct of antibiotic trials. A report of the Scientific Studies Committee of the Surgical Infection Society. Arch Surg 1987 Feb; 122(2):158-64.
  106. Tennenberg SD, Jacobs MP, Solomkin JS. Complement-mediated neutrophil activation in sepsis- and trauma-related adult respiratory distress syndrome. Clarification with radioaerosol lung scans. Arch Surg 1987 Jan; 122(1):26-32.
  107. Tennenberg SD, Bailey WW, Cotta LA, Brodt JK, Solomkin JS. The effects of methylprednisolone on complement-mediated neutrophil activation during cardiopulmonary bypass. Surgery 1986 Aug; 100(2):134-42.
  108. Antrum RM, Solomkin JS. Monocyte dysfunction in severe trauma: evidence for the role of C5a in deactivation. Surgery 1986 Jul; 100(1):29-37.
  109. Antrum RM, Solomkin JS. A rapid method for monocyte isolation and chemotaxis. J Clin Lab Immunol 1986 Mar; 19(3):139-42.
  110. Solomkin JS. Who should do the coding? JAMA 1986 Feb 7; 255(5):613-4.
  111. Solomkin JS, Cocchetto DM. Ceftazidime versus tobramycin plus ticarcillin in the treatment of soft-tissue infections. Clin Ther  1986; 9(1):123-34.
  112. Solomkin JS, Brodt JK, Zemlan FP. Degranulation inhibition. A potential mechanism for control of neutrophil superoxide production in sepsis. Arch Surg 1986 Jan; 121(1):77-80.
  113. Antrum RM, Solomkin JS. Improved erythrocyte sedimentation and leucocyte recovery with Dextran T500. Med Lab Sci 1986 Jan; 43(1):44-7.
  114. Solomkin JS, Brodt JK, Antrum RM. Suppressed neutrophil oxidative activity in sepsis: a receptor-mediated regulatory response. J Surg Res 1985 Oct; 39(4):300-4.
  115. Hurst JM, deHaven CB, Branson R, Solomkin JS. Combined use of high-frequency jet ventilation and induced hypothermia in the treatment of refractory respiratory failure. Crit Care Med 1985 Sep; 13(9):771-2.
  116. Antrum RM, Solomkin JS. Complement activation products and monocyte migratory function in trauma. Curr Surg 1985 Jul; 42(4):301-3.
  117. Solomkin JS, Fant WK, Rivera JO, Alexander JW. Randomized trial of imipenem/cilastatin versus gentamicin and clindamycin in mixed flora infections. Am J Med 1985 Jun 7; 78(6A):85-91.
  118. Solomkin JS, Cotta LA, Satoh PS, Hurst JM, Nelson RD. Complement activation and clearance in acute illness and injury: evidence for C5a as a cell-directed mediator of the adult respiratory distress syndrome in man. Surgery 1985 Jun; 97(6):668-78.
  119. Antrum RM, Solomkin JS. Regulation of monocyte function by complement activation products. J Surg Res 1985 May; 38(5):468-74.
  120. Dellinger EP, Wertz MJ, Meakins JL, et al. Surgical infection stratification system for intra-abdominal infection. Multicenter trial. Arch Surg 1985 Jan; 120(1):21-9.
  121. Ogle JD, Ogle CK, Noel JG, Solomkin JS, Alexander JW. Determination of C3b receptors on normal and patient polymorphonuclear neutrophils with C3b-coated fluorescent microspheres. Arch Surg 1985 Jan ; 120(1):104-9.
  122. Solomkin JS, Cotta LA, Brodt JK, Hurst JM. Regulation of neutrophil superoxide production in sepsis. Arch Surg 1985 Jan; 120(1):93-8.
  123. Meakins JL, Solomkin JS, Allo MD, Dellinger EP, Howard RJ, Simmons RL. A proposed classification of intra-abdominal infections. Stratification of etiology and risk for future therapeutic trials. Arch Surg 1984 Dec; 119(12):1372-8.
  124. Solomkin JS, Nelson RD, Chenoweth DE, Solem LD, Simmons RL. Regulation of neutrophil migratory function in burn injury by complement activation products. Ann Surg 1984 Dec; 200(6):742-6.
  125. Solomkin JS, Cotta LA, Ogle JD, et al. Complement-induced expression of cryptic receptors on the neutrophil surface: a mechanism for regulation of acute inflammation in trauma. Surgery 1984 Aug; 96(2):336-44.
  126. Solomkin JS, Meakins JL, Jr., Allo MD, Dellinger EP, Simmons RL. Antibiotic trials in intra-abdominal infections. A critical evaluation of study design and outcome reporting. Ann Surg 1984 Jul; 200(1):29-39.
  127. Solomkin JS, Cotta LA, Brodt JK, Hurst JW, Ogle CK. Neutrophil dysfunction in sepsis. III. Degranulation as a mechanism for nonspecific deactivation. J Surg Res 1984 May; 36(5):407-12.
  128. Solomkin JS, Simmons RL. Cellular and subcellular mediators of acute inflammation. Surg Clin North Am 1983 Apr; 63(2):225-43.
  129. Nelson RD, Chenoweth DE, Solomkin JS, Solem LD. Cytotaxin receptors on human neutrophils: modulation of C5a and peptide receptor number. Agents Actions Suppl 1983; 12:274-89.
  130. Solomkin JS, Flohr AM, Simmons RL. Indications for therapy for fungemia in postoperative patients. Arch Surg 1982 Oct ; 117(10):1272-5.
  131. Solomkin JS, Flohr A, Simmons RL. Candida infections in surgical patients. Dose requirements and toxicity of amphotericin B. Ann Surg 1982 Feb; 195(2):177-85.
  132. Solomkin JS, Jenkins MK, Nelson RD, Chenoweth D, Simmons RL. Neutrophil dysfunction in sepsis. II. Evidence for the role of complement activation products in cellular deactivation. Surgery 1981 Aug ; 90(2):319-27.
  133. Solomkin JS, Bauman MP, Nelson RD, Simmons RL. Neutrophils dysfunction during the course of intra-abdominal infection. Ann Surg  1981 Jul; 194(1):9-17.
  134. Solomkin JS, Flohr AB, Quie PG, Simmons RL. The role of Candida in intraperitoneal infections. Surgery 1980 Oct; 88(4):524-30.
  135. Solomkin JS, Simmons RL. Candida infection in surgical patients. World J Surg 1980 Jul; 4(4):381-94.
  136. Delaney JP, Solomkin JS, Jacobson ME, Doe RP. Surgical management of Cushing’s syndrome. Surgery 1978 Oct; 84(4):465-70.
  137. Solomkin JS, Mills EL, Giebink GS, Nelson RD, Simmons RL, Quie PG. Phagocytosis of Candida albicans by human leukocytes: opsonic requirements. J Infect Dis 1978 Jan; 137(1):30-7.
  138. Solomkin JS, Simmons RL, Quie PG. Serum opsonins for early diagnosis of disseminated candidiasis. Surg Forum 1977; 28:46-8.

And from my father, Mark M. Solomkin, M.D. (1911-1974), engaged in a busy private practice, but still contributing

1. Henken EM, Solomkin M, Edelstein SW, Horowitz BJ. Some complications of intra-uterine contraceptive devices. Conn Med 1969 Jul; 33(7):443-6.

2. Horowitz BJ, Solomkin M, Edelstein SW. The oversuppression syndrome. Obstet Gynecol 1968 Mar; 31(3):387-9.

3. Solomkin M, Allen MM, Edelstein SW. Ovarian pregnancy: a case report. Conn Med 1966 Oct; 30(10):725-6.

4. Solomkin M, Edelstein SW. METRONIDAZOLE–A REPORT OF A CLINICAL INVESTIGATION. Conn Med 1964 Oct; 28:737-9.

5. Solomkin M, ZIMMERMAN G. The use of intravenous oxytoxic infusions in caesarean sections. Conn Med 1962 Jul; 26:421-2.

6. Solomkin M, TAUBER WF. A study of constituents of the bloods of mother and infant at birth. Conn Med 1959 Mar; 23(3):141-5.

7. Solomkin M, TAUBER W. [An intra-abdominal giant Nabothian cyst]. Conn Med 1959 Jan; 23(1):27.

8. SCHLOSS WA, Solomkin M. Acute hydronephrosis of pregnancy. J Urol 1952 Dec; 68(6):885-92.

9. SCHLOSS WA, Solomkin M. Foreign body in the bladder; removal of thermometer with Stern-McCarthy resectoscope. J Am Med Assoc 1950 Jul 1; 143(9):804-5.

10. Solomkin M. Intra-epithelial carcinoma of the cervix. Conn State Med J 1950 May; 14(5):397-402.

11. TUCKER BE, Solomkin M, BRAMS B. A study of face presentation in the normal mature fetus. Surg Gynecol Obstet 1950 Feb ; 90(2):199-203.

12. BENARON H, Solomkin M, SLATE TA. Labor complicated by lymphopathia venereum. Q Bull Northwest Univ Med Sch 1949; 23(1):15-20.

 

 

Chapters

 

  1. Solomkin, J.S., Simmons, R.L.: Gas gangrene and other anaerobic soft tissue infections in Conn HL: Cur. Therapy 1981. Philadelphia: W.B. Saunder, 1981.
  2. Solomkin, J.S.: Phagocytosis of Candida albicans. In:Douglas, S.D., Quie, P.G. (eds): Investigations of Phagocytes in Disease. ChurchillLivingstone, New York, 1981. pp. 4852.
  3. Solomkin, J.S., Simmons, R.L.: Determinants of infection  the host. In:Clinical Surgery International, Vol. 4:318, 1982.
  4. Solomkin, J.S., Simmons, R.L.: Cellular and subcellular mediators of acute inflammation. Surgical Clinics of North America 63(2):225243, April, 1983.
  5. Solomkin, J.S.: Nutritional Management of Metabolic Stress. Cerra, F.B. (ed), North Chicago, Abbott Laboratories, 1983, pp 3748.
  6. Solomkin, J.S., Dougherty, S.H.: The Role of Enterococci and Candida in intraabdominal infection. In: Simmons, R.L. (ed) Topics in intraabdominal Surgical Infection. Part 2. AppletonCenturyCrofts, Connecticut, 1984 pp. 1,736.
  7. Solomkin, J.S., Dineen, P., Fry, D., Lou, M.A., Nichols, R.L.: A therapeutic conference: What’s new in thirdgeneration cephalosporins: prophylaxis. In:Dineen, P.(ed) Infections in Surgery Part 2. Infections in Surgery Associates, New York, New York, 1984, pp. 889896.
  8. Solomkin, J.S.: Rational microbiology for surgical infections. College of American Pathologists Conference 1984. In:The Role of Clinical Microbiology in CostEffective Health Care, James W. Smith, M.D.(ed), College of American Pathologists, Skokie, Illinois, 1985, pp. 33340.
  9. Solomkin, J.S.: Initial Antimicrobial Consideration. In:Hurst, J.M.(ed). Common Problems in Trauma. Yearbook Medical Publishers, Inc., Chicago and London, 1987, pp. 3946.
  10. Solomkin, J.S.: Opportunistic Infection. In:Hurst, J.M. (ed). Common Problems in Trauma. Yearbook Medical Publishers, Inc., Chicago and London, 1987, pp. 434439.
  11. Solomkin, J.S.: Use of new betalactam antibiotics for surgical infections. Surgical Clinics of North America 68(1):123, February, 1988.
  12. Solomkin, J.S.: Candida Infection. Approach to the Surgical Patient with Candidiasis. In:Douglas W. Wilmore, M.D. (ed). American College of Surgeons Care of the Surgical Patient. Section IX, Chapter 10. Scientific American, Inc., New York, New York, 1989, pp. 112.
  13. Christou, N.V., Solomkin, J.S.: Antibiotics. Antibiotic Therapy in Surgical Patients. In:Douglas W. Wilmore, M.D. (ed). American College of Surgeons Care of the Surgical Patient. Section IX, Chapter 3. Scientific American, Inc., New York, New York, 1989, pp. 133.
  14. Solomkin, J.S.: Aminoglycosides are still the gold standard for polymicrobial infections. In:Richard L. Simmons, M.D., Anthony O. Udeku, M.E. (eds). Debates in Clinical Surgery. Volume 2, Mosby-Year Book, Inc., Chicago, Illinois, pp. 135-143, 1990.
  15. Solomkin, J.S., Bass, R.C.: Neutrophil function in the inflammatory diseases of trauma and burn injury. In:David Dries, Richard Gamelli (eds). Trauma 2000, Chapter 10. R.G. Landes Company, Austin, Texas, pp. 85-90, 1992.
  16. Solomkin, J.S., Page, C.P.: Antibiotic Therapy. Current Practice of Surgery. Section IV:3. Levine, Copeland, Howard, Sugerman, Warshaw (eds). Churchill Livingstone, New York, New York, pp. 1-20, 1993.
  17. Solomkin, J.S.: Pathogenesis and management of Candida infection syndromes in non- neutropenic patients. In:Joseph S. Solomkin (ed). New Horizons. Volume 1(2), Williams & Wilkins and the Society of Critical Care Medicine, Baltimore, Maryland, pp. 202-213, 1993.
  18. Solomkin, J.S., Moulton, J.S.: Diagnosis and management of intraabdominal sepsis. Intensive Care Medicine, 1993.
  19. Solomkin, J.S., Miyagawa, C.I.: Principles of antibiotic therapy. Surgical Clinics of North America 74(3): 497-517, 1994.
  20. Solomkin, J.S., Anaissie, E.: Candida infections and candidemia. In:Donald E. Fry (ed) Surgical Infections, Little, Brown and Company, Boston, Massachusetts, pp. 577-589, 1994.
  21. Solomkin, J.S., Howard, R.J.: Antimicrobial Therapy. Antimicrobial Agents. In:Richard J. Howard, M.D., Richard L. Simmons, M.D. (eds). Surgical Infectious Diseases. Part V, Chapter 28. Appleton & Lange, East Norwalk, Connecticut, pp. 533-594, 1994.
  22. Solomkin, J.S., Anaissie, E.: Fungal Infection. Approach to the surgical patient at risk for candidiasis. American College of Surgeons Care of the Surgical Patient Section IX, Chapter 10. Scientific American, Inc., New York, New York, 1994 pp. 119.
  23. Solomkin, J.S., Burnett III, R.J., Cave, C.M., Tindal, C.J.: A Review: Neutrophils, Compartmentalized Cytokine Release, and Lung Injury. The Case for an Extravascular, Compartmentalized Basis for Organ Failure. Progress in Surgery. Vol. 20, Int. Symposium on Modulation of the Inflammatory Response in Severe Sepsis, Madrid. S. Karger Ag, Basel, Switzerland, Vol. 20, pp. 77-90, 1995.
  24. Solomkin, J.S., Hill, C.H.: Design Problems in Clinical Sepsis Trials. Progress in Surgery. Vol. 20, Int. Symposium on Modulation of the Inflammatory Response in Severe Sepsis, Madrid. Karger Ag, Basel, Switzerland, Vol. 20, pp. 59-66, 1995.
  25. Solomkin, J.S.: Antibiotics for Critically Ill Patients. In:John L. Cameron, M.D. (ed). Current Surgical Therapy, 5th Edition, MobsyYear Book, Inc., Philadelphia, Pennsylvania, pp.991-995, 1995.
  26. Solomkin, J.S., Moulton, J.S.: Diagnosis and Management of Intraabdominal Sepsis in: Rippe, J.N., Irwin, R.S., Fink, M.P., Cerra, F.B.: Intensive Care Medicine (3rd edition).Little, Brown, Inc., New Yoirk, 1996.
  27. Burnett,R.J., Bass,R.C., Neely,A.N.,Solomkin,J.S.: Lipopolysaccharide-Binding Proteins. In: Robinson,J.P.,Babcock,G.F.: Phagocyte Function: a guide for research and clinical evaluation. John Wiley & Sons, Inc., New York, 1998.
  28. Jawa, R.S, Solomkin, J.S.: Intra-abdominal Infections. . In:John L. Cameron, M.D. (ed). Current Surgical Therapy, 6th Edition, MobsyYear Book, Inc., Philadelphia, Pennsylvania, 1998.
  29. Solomkin, J.S., Wittmann, D.L., Barie, P.M.: Intra-abdominal infections. In: Seymour Schwartz (ed): Textbook of Surgery. William B. Saunders, Inc., New York, 1998.
  30. Jawa R.S., Quaid G.A., Solomkin J.S.: Cellular effectors of the septic process. In: Grenvik,A., Ayres,S.M., Holbrook,P.R.,Shoemaker,W.C.: Textbook of Critical Care,  4th edition. William B. Saunders, Inc., New York, 1998.
  31. Quaid, G.A., Solomkin J.S.: Nosocomial Infections in the ICU. In: Baue, A.E., Faist, E., Fry, D.E.: Multiple Organ Failure: Pathophysiology, Prevention, and Therapy. Springer-Verlag, New York, 2000.
  32. Solomkin, J.S.: Surgical Prophylaxis. In: Schlossberg, D: Current Therapy of Infectious Disease, 2nd edition. Mosby, St. Louis, 2001.
  33. Solomkin, J.S.:  Preoperative Bowel Preparation: Cameron, J.L: Current Surgical Therapy, 7th edition:.  Mosby, St. Louis, 2001.
  34. Solomkin, J.S., Anaissie, EmJ., Albair, B.B.: Candida infections in the intensive care unit.  In: Vincent, J., Carlet, J., Opal S.M.:  The Sepsis Text,  Norwell, Massachusetts, 2002.
  35. Dignani, M.C., Solomkin, J.S., Anaissie, E.J.: Candida. In: Anaissie, E.J., McGinnis, M.R., Pfaller, M.A.: Clinical Mycology, Churchill Livingstone, Philadelphia, Pennsylvania, 2003. 
  36. Solomkin, J.S.:  Treatment of Intra-Abdominal Infections.  In:  Hooper, D.C., Rubinstein, E.:  Quinolone Antimicrobial Agents. 3rd Edition. Washington, DC, 2003.
  37. Solomkin, J.S., C. Edlund: Intra-abdominal Infections. Lectures in Hospital Infections. Part Three. London, 2006.
  38. Husted, T.L., Mueller, E.W., Lasky, T.M., Jafri, M.A., Solomkin, J.S.: Diagnosis and Management of Intra-abdominal Sepsis. In: Rello, J., Kollef, M., Diaz, E., Rodriguez, A.: Infectious Diseases in Critical Care. 2nd Edition. New York, NY, 2007.
  39. Solomkin, J.S.: Perioperative Antimicrobial Prophylaxis. In: Fischer, J.E.: Mastery of Surgery. 5th Edition. Philadelphia, PA 2007.
  40. Husted, T.L., Mueller, E.W., Lasky, T.M., Jafri, M.A., Solomkin, J.S.: Diagnosis and Management of Intraabdominal Sepsis. In: Irwin, R.S., Rippe, J.M.: Irwin and Rippe’s Intensive Care Medicine. 6th Edition. Philadelphia, PA, 2008.

ABSTRACT PRESENTATIONS

  1. Solomkin, J.S., Quie, P.G., Simmons, R.L.: Serum opsonins for the early diagnosis of disseminated candidiasis. American College of Surgeons (Surgical Forum), Oct. 1015, 1975.
  2. Delaney, J.F., Solomkin, J.S., Jacobson, M.E., Doe, R.P.: Surgical management of Cushing’s syndrome. Central Surgical Association, March 1216, 1976.
  3. Solomkin, J.S., Flohr, A., Quie, P.G., Simmons, R.L.: Candida peritonitis: therapeutic considerations. Central Surgical Association, March 1215, 1980.
  4. Solomkin, J.S., Nelson, R.D., Simmons, R.L.: General surgical patients as immunocompromised hosts: identification of a high risk group for fungal infection. International Symposium on Infections in the Immunocompromised Host (the Netherlands), June 15, 1980.
  5. Solomkin, J.S., Jenkins, M., Chenoweth, D.E., Nelson, R.D.: Complement activation as the basis of neutrophil dysfunction in intraabdominal infection. Society of University Surgeons, February 1214, 1981.
  6. Solomkin, J.S., Solem, L.D., Chenoweth, D.E., Bauman, M., Nelson, R.D., Simmons, R.L.: The role of tissuephase complement activation in the pathogenesis of neutrophil dysfunction in thermally injured patients. American Burn Association, April 24, 1981.
  7. Solomkin, J.S., Simmons, R.L.: Indications for therapy of fungemia in postoperative patients. Western Surgical Association, November 1619, 1981.
  8. Bjornson, H.S., Solomkin, J.S.: Cytomegalovirus as a cause of unexplained fever in surgical patients. Surgical Infection Society, May 910, 1983.
  9. Ogle, C.K., Solomkin, J.S., Guo, X., Ogle, J.D., Alexander, J.W.: Production of C3 by patient monocytes. XVIII Congress of European Society for Surgical Research (Athens, Greece), May 1518, 1983.
  10. Solomkin, J.S., Cotta, L., Hurst, J.M., Joffe, S.N.: Does complement activation in acute pancreatitis result in respiratory failure? Pancreas Club, Inc. 1983 Annual Meeting, May 23, 1983.
  11. Solomkin, J.S., Cotta, L., Hurst, J.M., Joffe, S.N.: Does complement activation in acute pancreatitis result in respiratory failure? The Surgical Forum on Fundamental Surgical Problems, October 17, 1983.
  12. Solomkin, J.S., Bjornson, H.S.: A randomized trial of ceftazidime and tobraticar in serious gramnegative softtissue and pulmonary infections. Interscience Conference of Antimicrobial Agents and Chemotherapy, October 24, 1983.
  13. Allo, M.D., Dellinger, E.P., Howard, R.J., Meakins, J.L., Solomkin, J.S., Simmons, R.L.: Surgical infection stratification (SIS): a scheme to classify and stratify intraabdominal infections by etiology and severity. Interscience Conference of Antimicrobial Agents and Chemotherapy, October 24, 1983.
  14. Solomkin, J.S., Cotta, L., Ogle, C., Hurst, J.M.: PMN dysfunction in sepsis: role of oxide formation and receptor loss. Association for Academic Surgery, November 25, 1983.
  15. Solomkin, J.S., Ogle, C.G., Ogle, J.D., Alexander, J.W.: Expression of cryptic phagocytic and chemotactic receptors as a mechanism of regulation of neutrophil function in trauma patients. Society of University Surgeons, February 911, 1984.
  16. Solomkin, J.S., Brodt, J.K., Cotta, L.A., Ogle, C.G.: Defective neutrophil superoxide production in severe sepsis: a manifestation of prior in vivo degranulation. Surgical Infection Society, April 30May 1, 1984.
  17. Dellinger, P., Wertz, M.J., Meakins, J.L., Allo, M.D., Solomkin, J.S., Howard, R.J., Simmons, R.L.: Surgical infection stratification in intraabdominal infection. Surgical Infection Society, April 30May 1, 1984.
  18. Ogle, J.D., Ogle, C.K., Noel, J.G., Solomkin, J.S., Alexander, J.W.: Determination of C3b receptors on normal and patient PMN with C3bcoated fluorescent microspheres. Surgical Infection Society, April 30May 1, 1984.
  19. Cotta, L.A., Solomkin, J.S., Brodt, J.K., Ogle, C.G.: Neutrophil FMLP receptor status and function in intraabdominal sepsis. Third International Symposium on Infection in the Immunocompromised Host, June 2428, 1984.
  20. Solomkin, J.S., Cotta, L.A., Satoh, P.S.: Complement neutrophil interactions in acute surgical illness. Third International Symposium on Infection in the Immunocompromised Host, June 2428, 1984.
  21. Fant, W.K., Solomkin, J.S., Rivera, J.: Increased volume of distribution in abdominal infection. Interscience Conference on Antimicrobial Agents and Chemotherapy, October 810, 1984.
  22. Solomkin, J.S., Fant, W.K., Rivera, J., Bjornson, H.S.: A phase II/III trial of primaxin (P) (MK0787/MK0791) vs. gentamicin/clindamycin (G/C) for polymicrobial sepsis. Interscience Conference on Antimicrobial Agents and Chemotherapy, October 810, 1984.
  23. Solomkin, J.S., Lentnek, A.L.: A randomized multicenter trial of ceftizoxime (CFZ) vs. tobramycin/clindamycin (T/C) for intraabdominal infection. Interscience Conference on Antimicrobial Agents and Chemotherapy, October 810, 1984.
  24. Solomkin, J.S., Brodt, J.K., Cotta, L.A.: Regulation of neutrophil superoxide production in sepsis. Association for Academic Surgery, October 31November 3, 1984.
  25. Antrum, R.M., Solomkin, J.S.: Regulation of monocyte function by complement activation products. Association for Academic Surgery, October 31November 3, 1984.
  26. Solomkin, J.S., Sundberg, S., Fant, W.K., Rivera, J.: A randomized multicenter trial of ceftizoxime (CFZ) vs. tobramycin/clindamycin (T/C) for intraabdominal infection. Fourth Annual Ohio Conference on Clinical Pharmacy and Clinical Pharmacology, October 6, 1984.
  27. Fant, W.K., Hurford, B.S., Solomkin, J.S., Rivera J.: A randomized trial of ceftazidime vs. tobramycin/ticarcillin for presumed gramnegative soft tissue and pulmonary infections. Fourth Annual Ohio Conference on Clinical Pharmacy and Clinical Pharmacology, October 6, 1984.
  28. Antrum, R.M., Solomkin, J.S.: Complement activation products regulate monocyte chemotaxis in trauma. Society of University Surgeons Residents Meeting, February 5, 1985.
  29. Solomkin, J.S., Brodt, J.K.: Secondary granule translocation inhibition: a proposed mechanism for neutrophil dysfunction in sepsis. Surgical Infection Society, April 2930, 1985.
  30. Solomkin, J.S., Brodt, J.K., Zemlan, F.P.: Uptake of clindamycin by human neutrophils (PMN) is not mediated by adenosine or clindamycin receptors. Interscience Conference on Antimicrobial Agents and Chemotherapy, September 29October 2, 1985.
  31. Tennenberg, S.D., Bailey, W.W., Benzing III, G., Solomkin, J.S.: Lack of evidence for complementmediated neutrophil activation in cardiopulmonary bypass with steroid pretreatment. Society of University Surgeons Meeting, February 1315, 1986.
  32. Tennenberg, S.D., Jacobs, M.P., Baughman, R.P., Solomkin, J.S.: Complementmediated neutrophil activation in sepsis and traumarelated ARDS: clarification with in vivo radioaerosol alveolarcapillary permeability scans. Surgical Infection Society, April 2122, 1986.
  33. Tennenberg, S.D., Jacobs, M.P., Baughman, R.P., Hurst, J.M., Solomkin, J.S.: Increased pulmonary alveolarcapillary permeability in patients at risk for the adult respiratory distress syndrome. Society of Critical Care Medicine Meeting, May 2731, 1986.
  34. Tennenberg, S.D., Zemlan, F.P., Brodt, J.K., Solomkin, J.S.: Characterization of Nformyl methionyl leucyl phenylalanine receptors in sepsis. 4th International Symposium on Infections in the Immunocompromised Host, June 1519, 1986 (poster presentation).
  35. Tennenberg, S.D., Kemp, C.L., Solomkin, J.S.: Neutrophil superoxide production in patients at risk for and experiencing the adult respiratory distress syndrome. 4th International Symposium on Infections in the Immunocompromised Host, June 1519, 1986 (poster presentation).
  36. Tennenberg, S.D., Bailey, W.W., Cotta, L.A., Brodt, J.K., Solomkin, J.S.: Methylprednisolone prevents complementmediated neutrophil activation in vivo and in vitro. 4th International Symposium on Infections in the Immunocompromised Host, June 1519, 1986 (poster presentation).
  37. Tennenberg, S.D., Zemlan, F.P., Solomkin, M.D.: Altered neutrophil oxidative metabolism and receptor status in sepsis and traumarelated adult respiratory distress syndrome. American College of Surgeons (Surgical Forum), October 1924, 1986.
  38. Tennenberg, S.D., Solomkin, J.S.: Surface receptor mobilization in complementmediated neutrophil activation: characterization and effects of methylprednisolone. Association for Academic Surgery, November 58, 1986 (poster presentation).
  39. Tennenberg, S.D., Kurucz, D.S., Solomkin, J.S.: Further characterization of the neutrophil’s postactivation state in thermal injury. American Burn Association, 19th Annual Meeting, April 29May 2, 1987 (abstract and presentation).
  40. Tennenberg, S.D., Solomkin, J.S.: Activation of neutrophils by cachectin/tumor necrosis factor: Priming of Nformylmethionylleucylphenylalanineinduced oxidative responsiveness via receptor mobilization. Ohio Chapter of the American College of Surgeons, 32nd Annual Meeting, April 30May 2, 1987 (abstract and presentation).
  41. Tennenberg, S.D., Solomkin, J.S.: Cachectin/tumor necrosis factor primes the oxidative activity of neutrophils via receptor mobilization. American Federation of Clinical Research, 1987 National Meeting, May 14, 1987 (abstract and presentation).
  42. Tennenberg, S.D., Solomkin, J.S.: Neutrophil activation in sepsis: The relationship between FMLP receptor mobilization and oxidative activity. Surgical Infection Society, 7th Annual Meeting, May 1112, 1987 (abstract and presentation).
  43. Tennenberg, S.D., Tindal, C., Roper, E., Noel, G., Ogle, J.D., Solomkin, J.S.: Platelet activating factor primes the oxidative responsiveness of neutrophils: A potential role for platelet activating factor in hostdefense and oxidant tissue injury. Association for Academic Surgery, November 14, 1987 (abstract).
  44. Tennenberg, S.D., Solomkin, J.S.: Neutrophil activation in sepsis: The relationship between fmetleuphe receptor mobilization and oxidative activity. Ohio Chapter of the American College of Surgeons, 33nd Annual Meeting, May 57, 1987 (abstract and presentation).
  45. Tennenberg, S.D., Solomkin, J.S.: Activation of neutrophils by tumor necrosis factor: Priming of fmetleupheinduced oxidative responsiveness via receptor mobilization without degranulation. 5th International Symposium on Infections in the Immunocompromised Host, June 59, 1988 (abstract, poster and presentation).
  46. Tennenberg, S.D., Clardy, C.W., Bailey, W.W., Solomkin, J.S.: Complement activation during cardiopulmonary bypass is not associated with increased pulmonary epithelial permeability. Association for Academic Surgery, November 1619, 1988 (abstract).
  47. Tindal, C.J., Solomkin, J.S.: Characterization of the direct and indirect effects of tumor necrosis factor (TNF) on human neutrophils. Federation of American Societies for Experimental Biology Meeting, March 1923, 1989 (abstract and poster session).
  48. Solomkin, J.S.: New approaches to serious infections in the surgical patient. Intra-abdominal infection: a medical surgical challenge symposium, February 10-11, 1990, Innsbruck, Austria.
  49. Solomkin, J.S., Cave, C.M.: Activation of circulating human monocytes in infections. Surgical Infection Society, June 14-16, 1990 (poster presentation).
  50. Solomkin, J.S., Fant, B.S., Fant, W.K.: The relationship of aminoglycoside pharmacokinetics to APACHE II Scores in surgical patients with documented gram-negative intra-abdominal infections. Interscience Conference on Antimicrobial Agents and Chemotherapy, October 21-24, 1990 (abstract and presentation).
  51. Solomkin, J.S., Tindal, C., Cave, C., Dorsey, A.: Activation by granulocyte-colony stimulating factor for neutrophil oxidative responses involves regulation by G proteins. 28th Annual Meeting of Society for Leukocyte Biology, September 28-October 1, 1991 (poster presentation).
  52. Solomkin, J.S., Bell, R., Bjornson, H.S., Nussbaum, M., McFadden D., Magan, L.: Candida in peripancreatic infection: a clinical experience. Pancreas Club Meeting, May 9, 1994. Hyams, D.M., Steele, P.E., Distler, C., Hariharan, J., Solomkin, J.: Immunosuppressive activity of an envelope protein fragment derived from the tumor-associated human endogenous retroviral sequence clone 4-1. American College of Surgeons Forum, October 14, 1992 (abstract and presentation).
  53. Solomkin, J.S., Tindal, C.: IL-8 modulates TNF-α receptor number on human neutrophils and TNF-α induced fibronectin adherence. Society for Leukocyte Biology, December 2-5, 1992 (poster presentation).
  54. Bass, R.C., Solomkin, J.S., Cave, C., Tindal, C., Ogle, C., Ogle, J.: Complement is a required cofactor for neutrophil priming in response to LPS/serum. Society for Leukocyte Biology, December 2-5, 1992 (poster presentation).
  55. Solomkin, J.S., Bass, R.C., Bjornson, H.S., Ogle, C.K., Babcock, G.F.: Intravascular IL-8 down-regulates PMN responses to TNF-alpha during endotoxemia. Surgical Infection Society, April 28-May 1, 1993, Baltimore, Maryland (abstract and presentation).
  56. Baughman, R., Gunther, K., Solomkin, J.: Serial bronchoalveolar lavage in sepsis associated adult respiratory distress syndrome. 4th International Conference on Bronchoalveolar Lavage, Umea, Sweden, June, 1993.
  57. McFadden, D., Fink, A., Nussbaum, M., Bjornson, S., Bell, R., Sewak, L., Solomkin, J.: Candida in pancreatic infection: a clinical experience. American Pancreatic Association, November 45, 1993, Chicago, Illinois.
  58. Solomkin, J.S., Tindal, C.J., Neely, A., Lyden, C.: BPI pretreatment suppresses LPSinduced macrophage TNFAlpha production by a receptordirected mechanism. The Immunocompromised Surgical Patient: Mechanisms and therapy in trauma and burns Symposium, January 1519, 1994, Snowbird, Utah.
  59. Solomkin, J.S.: The crucial cellular element for the initiation of MODS/MOF:  PMN. 3rd International Congress on the Immune Consequences of Trauma, Shock and Sepsis Mechanisms and Therapeutic Approaches, March 25, 1994, Munich, Germany (abstract and presentation).
  60. Solomkin, J.S.: Utility of severity scoring systems in determining outcome from infection: a critical view. 3rd International Congress on the Immune Consequences of Trauma, Shock and Sepsis Mechanisms and Therapeutic Approaches, March 25, 1994, Munich, Germany (abstract and presentation).
  61. Burnett, R., Cave, C., Tindal, C., Solomkin, J.S.: IL-8 inhibits neutrophil tyrosine kinase activity and H2O2 production. 17th Annual Conference on Shock, June 5-8, 1994, Big Sky, Montana (abstract and presentation).
  62. Solomkin, J.S., Reinhart, H.: Results of a trial of IV+PO Ciprofloxacin/Metronidazole (C/M) vs Imipenem (I) for complicated intraabdominal infections. 34th ICAAC Meeting, October 47, 1994, Orlando, Florida (abstract and presentation).
  63. Solomkin, J.S., Cave, C., Tindal, C., Rechtman, D.: Effect of monophosphoryl lipid A (MPLA) on neutrophil chemotaxis and IL8 receptors. 34th ICAAC Meeting, October 47, 1994, Orlando, Florida (abstract and poster presentation).
  64. Burnett, R.J., Tindal, C.J., Lyden, C.A., Neely, A.N., Solomkin, J.S.: Bactericidal/permeability increasing protein (BPI) binds to THP1 cells in a nonCD14 mediated fashion and inhibits LPS induced TNF production. Accepted for presentation at Residents’ Program of SUS, February 11, 1994, Denver, Colorado.
  65. Burnett, R.J., Dellinger, E.P., Reinhart, H.R., Bohnen, J.M., James, L.E., Solomkin, J.S.: Definition of the role of Enterococcus in intraabdominal infection: results of a prospective randomized trial. Central Surgical Meeting, March 911, 1995, Cleveland, Ohio.
  66. Solomkin, J., Reinhart, H.: Results of a trial of IV + PO Ciprofloxacin/Metronidazole (CIP/MTZ) vs Imipenem (IMI) for complicated intra-abdominal infections. 7th European Congress of Clinical Microbiology and Infectious Diseases Meeting in Vienna, Austria, March 29, 1995.
  67. Burnett, R.J., Lyden, C.A., Tindal, C.J., Marra, M.N., Solomkin, J.S.: The mononuclear cell line THP1 binds and internalizes bactericidal/permeabilityincreasing protein (BPI) in the presence and absence of LPS by nonreceptor mediated pinocytosis. Surgical Infection Society, April 1922, 1995, Louisville, Kentucky.
  68. Solomkin, J.S., Echols, R., Haverstock, D. and Intraabdominal Study Group: Sequential treatment of intraabdominal infection: a clinical trial of ciprofloxacin (CIP) plus metronidazole (MTZ) vs imipenem (IMI). 19th International Congress of Chemotherapy, July 16-21, 1995, Montreal, Quebec, Canada.
  69. Solomkin, J., Reinhart, H., and the Intraabdominal Infections Study Group: Results of a trial of IV + Ciprofloxacin/Metronidazole (CIP/MTZ) vs Imipenem (IMI) for complication intraabdominal infections. 2nd International Conference on Sepsis in the ICU, June 27-29, 1995, Maastricht, The Netherlands.
  70. Solomkin, J.S., Echols, R., Haverstock, D. and the Intraabdominal Study Group: Sequential treatment of intraabdominal infection: a clinical trial of ciprofloxacin (CIP) plus metronidazole (MTZ) vs imipenem (IMI). International Congress of Chemotherapy, Montreal July 16-21, 1995.

 

  1. Heard, S.O., Napolitano, L., Fink, M., Dries, D., Gamelli, R., Solomkin, J., Joshi, M., Gerrard, K., Trask, A., Fabian, T., Hudson, L., Logan, E., and the G-CSF Study Group. Preventing nosocomial infections in intubated patients with brain injury or hemorrhage: role of granulocyte colony-stimulating factor (G-CSF, filgrastim). 61st Annual American College of Chest Physicians, October 29-November 2, 1995, New York, New York.
  2. Jawa R.S., Cave C.M., Solomkin, J.S.: Genetic regulation of the IL-8 receptor A and B on human neutrophils by TNFα. 5th Joint Meeting, Leukocyte Biology Society, Verona Italy October 14-16, 1996.
  3. Williams, M.A., Jawa, R.S., Cave, C.M., and Solomkin, J.S.:  Effect of TNF and C5a on Neutrophil (PMN) Interleukin-8 (IL-8) Receptor/Ligand Interactions.  ABSTRACT.  Journal of the Association for Academic Minority Physicians, 1996.
  4. Williams, M.A., Cave, C.M., Jawa, R.S., and Solomkin, J.S.:  CXC Chemokines Differentially Modulate Tumor Necrosis Factor  (TNF) Induced Hydrogen Peroxide (H2O2) Production in Human Neutrophils (PMNs).  POSTER.  Student Ntl. Medical Assoc., 1997.
  5. Williams, M.A., Cave, C.M., Jawa, R.S., and Solomkin, J.S.:  Neutrophil Activating Peptide 2 (NAP-2) Selectively Modulates Human Neutrophil CXCR2 Interleukin-8 (IL-8) Receptor Mediated Functions.  ORAL PRESENTATION.  Howard Hughes Medical Institute Annual Fellows Scientific Meeting, 1997.
  6. Williams, M.A., Cave, C.M., Jawa, R.S., and Solomkin, J.S.:  Hydrogen Peroxide (H2O2) Production by Neutrophils (PMNs) Adherent to Fibronectin (FN) is Mediated via 1 Integrins.  POSTER.  Shock Society Annual Conference, 1997.
  7. Jawa, R.S., Cave, C.M., Williams, M.A., Robinson, C.T., and Solomkin, J.S.:  Restriction of Human Neutrophil (PMN) Responses to Cytokines by Neutrophil Activating Peptide 2 (NAP2). POSTER. Shock Society Annual Conference, 1997.
  8. Jawa, R.S., Cave, C.M., Robinson, C.T., Williams, M.A., and Solomkin, J.S.: Growth Related Oncogene a (GRO) Selectively Modulates Human Neutrophil (PMN) Responses to Inflammatory Cytokines. ORAL.  Association for Academic Surgeons, 1997.
  9. Williams, M.A., Robinson, C.T., Cave, C.M. and Solomkin, J.S.:  A Role for Homotypic Adhesion in 1 Integrin Mediated Functioning of Normal Human Neutrophils.  POSTER. FASEB, Experimental Bio. 1998.
  10. Williams, M.A., Robinson, C.T., Cave, C.M., Jawa, R.S., and Solomkin, J.S.: CXC Chemokines Differentially Modulate Neutrophil Responses to Tumor Necrosis Factor . POSTER. Society for Leukocyte Biology, 1998.
  11. Williams, M.A., Cave, C.M., Robinson, C.T., Quaid, G and Solomkin, J.S.:  Disparate Regulation of Neutrophil Proinflammatory Functioning by CXCR2-Specific Chemokines.  ORAL. Surgical Infections Society, 1999.
  12. Quaid, G.Q., Cave, C.M., Robinson, C.T., Williams, M.A. and Solomkin, J.S.:  Proximal Regulation of CXCR2 Receptor Expression and Function on Neutrophils in Trauma Victims.  ORAL. Surgical Infections Society, 1999.
  13. Williams, M.A., Cave, C.M., Quaid, G., Solomkin, J.S.: Activation of Agonist-Speicific Signaling Pathways by CXCR2-Selective Chemokines.  POSTER.  Amer. Assoc. of Immunol. 2000.
  1. Quaid, G.Q., Cave, C.M., Robinson, C.T., Williams, M.A. and Solomkin, J.S.:  TNFα and IL-8 Regulate Human Neutrophil NADPH Oxidase Expression by Different Mechanisms. Surgical Infection Society. Snowbird, May 2, 2001.
  2. Quaid G, Williams M, Cave C, Solomkin J. CXCR2 regulation of tumor necrosis factor-alpha adherence-dependent peroxide production is significantly diminished after severe injury in human neutrophils. Central Surgical Association. Tuscon AZ, Mar 2001.
  3. J.S. Solomkin, A. Yellin, O. Rotstein, et al: Results of a Double Blind, Randomized Comparative Phase III Trial of Ertapenem vs Piperacillin/tazobactam in the Treatment of Complicated Intraabdominal Infections. Surgical Infection Society. Snowbird, May 2, 2001.
  4. D. Spight, J. Solomkin. It’s Not the Bugs that Kill You: Proof of Principles? Crit Care Med 2002; 30(12 Suppl):A10.
  5. S. Parbhoo, M. Gearhart, M. Dusing, S. Pass. Prospective Evaluation of Diagnostic and Treatment Protocol for Ventilator-Associated Pneumonia (VAP) in SICU Patients. Crit Care Med 2002; 30(12 Suppl):A116.
  6. Yoo, J., Nichols, A., Solomkin, J., Matlin, K., Matthews, J.B.: Bryostatin-1 attenuates TNF-induced intestinal barrier dysfunction: role of novel PKC isoforms and TNF-R1 shedding. American College of Surgeons, September 2002, S10.
  7. Spight, D., Denenberg, A., Solomkin, J., Shanley, T.: IL-10 regulation of lung l-к-kinase activity in CLP. American College of Surgeons, September 2002, S90.
  8. Solomkin, J.: Proposed Guidelines for Antibiotic Therapy in Cholecystitis and Cholangitis. International Consensus Meeting of the Management of Acute Cholecystitis and Cholangitis, April 2006.
  9. Solomkin, J.: Pre-emptive Treatment of Fungal Infections in Surgery. Surgical Infection Society, Europe, May 2006.
  10. Butler, KL, Lu, EJ, Solomkin, JS, Tsuei, BT, Attaran, A, Tannous, G, Johannigman, J: Risk Factors for Relapse of Ventilator-Associated Pneumonia in Trauma Patients. American Association for the Surgery of Trauma, September 2007, S3B.

 

POST GRADUATE COURSES:

 

  1. University of Cincinnati, Department of Surgery, Shriners Burn Institute Seminar: The Use of Antibiotics and Antibacterial Agents. Cincinnati, Ohio, April 1, l983.
  2. American College of Surgeons PostGraduate Course: Immunologic Abnormalities Predisposing to Infection and Their Prevention. Chicago, Illinois, Oct. 26, 1982.
  3. American College of Surgeons (Ohio Chapter): IntraAbdominal SepsisAntibiotics. Warren, Ohio, May 6, 1983.
  4. University of Cincinnati, Department of Surgery, Shriners Burn Institute Seminar: Initial Local Care and Topical Agents. Cincinnati, Ohio, September 2223, 1983.
  5. University of Cincinnati, Department of Surgery Symposium: Antibiotic Selection for Surgical Infections: Where Do the Newer Cephalosporins Fit? Cincinnati, Ohio, December 3, 1983.
  6. Critical Care Medicine Update 1984, The Johns Hopkins University School of Medicine: Fungal Infections in the Intensive Care Unit. Baltimore, Maryland, March 26, 1984.
  7. The American Society of Abdominal Surgeons PostGraduate Course on Antibiotics and Surgical Infections: Role of Enterococci and Candida in Intraabdominal Infection. New Orleans, Louisiana, April 1, 1984.
  8. Creighton University School of Medicine, Departments of Medicine and Medical Microbiology Symposium: Developments in Diagnosis and Therapy of Infectious Diseases. Omaha, Nebraska, April 13, 1984.
  9. Washington University in St. Louis, St. Louis University Medical Center Abdominal Trauma Seminar: Prevention and Treatment of Sepsis Following Abdominal Trauma. St. Louis, Missouri, September 14, 1984.
  10. An Evening with the Professors: Peritonitis. II. Organ Failure Syndrome in Peritonitis. Minneapolis, Minnesota, October 15, 1984.The Ohio Chapter, American College of Surgeons Meeting: Fungal Infections in General Surgery. Cleveland, Ohio, May 10, 1985.
  11. The South Carolina Chapter of the American College of Surgeons Meeting: New approaches to surgical management of intraabdominal sepsis; Use of Imipenem in mixed flora infections. Charleston, South Carolina, September 6, 1985.
  12. American College of Surgeons Plenary Lecture: Antibiotics in the management of intraabdominal sepsis. Chicago, Illinois, October 1318, 1985.
  13. American College of Surgeons Postgraduate Course: Antifungals. Chicago, Illinois, October 1318, 1985.
  14. American College of Surgeons 1986 Spring Meeting Postgraduate Course: Neutrophils and Complement. Vancouver, British Columbia, April 1317, 1986.
  15. American College of Surgeons Postgraduate Course: Prevention and treatment of yeast and fungal infections in the postoperative compromised patient. New Orleans, Louisiana, October 1924, 1986.
  16. The Ohio Chapter, American College of Surgeons Meeting: Management of Infection in the SICU. Dayton, Ohio, May 2, 1987.
  17. The Thirteenth Annual Conference on Shock: Regulation of Neutrophil Function Following Burns and Trauma. Durango, Colorado, June 8-11, 1990.
  18. American College of Surgeons Fall Meeting Postgraduate Course: Management of Candida infections in surgical patients. San Francisco, California, October 7-12, 1990.
  19. Wayne State University Annual Critical Care Medicine Symposium, Detroit, Michigan, March 16, 1991.
  20. Fifteenth Triennial Meeting of the University of Cincinnati Graduate Surgical Society. Scientific presentation: Use of Biological Products in Sepsis. Cincinnati, Ohio, October 18, 1991.
  21. American College of Surgeons Postgraduate Course: Critical Care: Multiple Organ Failure: Antimicrobials. Chicago, Illinois, October 20-25, 1991.
  22. American College of Surgeons Postgraduate Course: Basic Principles for the Practicing Surgeon. Therapeutics Antibiotics: The Right Choice for the Right Problem at the Least Price. Orlando, Florida, March 22-25, 1992.
  23. Annual Jesse P. Eddy Symposium, Rhode Island Chapter of the American College of Surgeons Providence Surgical Society, Providence, Rhode Island, April 21, 1992.
  24. American College of Surgeons Postgraduate Course: Surgical Basic Science: Cytokines – Growth Factors: Basic Concepts and Clinical Relevance. Function of Neutrophils in the Cytokine Network. New Orleans, Louisiana, October 11-16, 1992.
  25. American College of Surgeons Postgraduate Course: Critical Care: ICU Care Controversies. Critically Ill Surgical Patients with Sepsis Syndrome But Without an Obvious Source of Infection Should be Treated with Empirically Broad Spectrum Antimicrobials. New Orleans, Louisiana, October 11-16, 1992.
  26. Florida Chapter of American College of Surgeons Meeting. Antibiotics and Biotechnology in Surgical Infections. Amelia Island, Florida, November 20-22, 1992.
  27. Central Surgical Society Meeting. Scientific presentation: Neutrophil adherence: sepsis and ARDS. March 4, 1993, Cincinnati, Ohio.
  28. Management of opportunistic mycotic infections: the 1990s and beyond. Candida infections in surgical patients. May 11, 1993, Houston, Texas, .
  29. Current Issues in Sepsis Conference, University of California, Davis. Scoring systems in sepsis. May 15, 1993, Oakland, California.
  30. Evolving Trends in Therapy for Surgical Infections Conference. Management of Candida infections syndromes in non-neutropenic patients. October 10, 1993, San Francisco, California.
  31. American College of Surgeons Postgraduate Course: Critical Care of the Trauma Patient: Why We Do What We Do. Peritoneal cultures – are they clinically useful in generalized peritonitis? (YES). San Francisco, California, October 10-15, 1993.
  32. Clinical Applications of Biologic Mediators in Severe Infections. Sepsis: Pathogenesis and Mediators of Injury. Tucson, Arizona, November 1114, 1993.
  33. Focus on Fungal Infections 4. Candidiasis in the setting of the intensive care unit. Houston, Texas, March 24-25, 1994.
  34. Innovations in the Management of Candidemia Symposium. Management of Candidal infections in the surgical patient. San Antonio, Texas, September 9-10, 1994.
  35. New Jersey Chapter of the Society of Critical Care Medicine. Critical Care Cross-fire: Should Multisite Fungal Colonization be Treated? New Brunswick, New Jersey, October 6, 1994.
  36. American College of Surgeons Postgraduate Course: Controversies in the Management of Surgical Infection. Antibiotic Controversies: CON: Fluconazole is adequate treatment for Candida infection. Chicago, Illinois, October 9-14, 1994.
  37. Cleveland Society of Critical Care, Cleveland, Ohio. November 14, 1994.
  38. Fifth Annual Critical Care Symposium, Lehigh Valley Hospital, Management of Candida in surgical patients. Allentown, Pennsylvania, February 24, 1995.
  39. Focus on Fungal Infections 5. Early presumptive therapy, a historical perspective and update. San Francisco, California, March 9-10. 1995.
  40. Contemporary Problems with Surgical Infections. Universities of Louisville and Cincinnati. Louisville, Kentucky and Cincinnati, Ohio, March 24-25, 1995.
  41. Multispecialty Focus on Candida Infections. Baylor College of Medicine. Houston, Texas, May 13, 1995.
  42. Controversies in Abdominal Trauma Symposium. Intra-abdominal infections post trauma. Yale University School of Medicine. New Haven, Connecticut, May 26, 1995.
  43. Missouri Chapter of American College of Surgeons Meeting. Lake Ozark, Missouri, June 16, 1995.
  44. Second Annual University of Minnesota Critical Care Course. Advances and controversies in critical care symposium. Minneapolis, Minnesota, July 7-8, 1995.
  45. Outcome determinations in the treatment of intra-abdominal infection. Clinical Trials: Issues in Surgical Infection, Surgical Infection Society, Pittsburgh, May 3, 1997
  46. Antibiotic prophylaxis for gastrointestinal surgery. Post-graduate Course, American College of Surgeons, Chicago, Illinois October 7, 1997.
  47. Rational anti-infective therapy. Post-graduate Course, American College of Surgeons, Orlando, FL, October 26, 1998.

 

Stopped recording after 1998 (loss of vanity)

VISITING PROFESSOR PRESENTATIONS

 

  1. Southwestern Michigan Area Health Education Center Surgical Residency Program, Surgical Journal Club and Grand Rounds: Prophylaxis and Therapy of Candida Infection. Kalamazoo, Michigan, Jan. 27, 1983.
  2. Grand Rapids Area Medical Education Consortium, Grand Rounds: Role of 3rd Generation Cephalosporins in Peritonitis. Grand Rapids, Michigan, March 1617, 1983.
  3. Case Western Reserve University Visiting Professor. Cleveland, Ohio, November 10, 1983.
  4. McGill University Visiting Professor. Montreal, Canada, August 1517, 1984.
  5. Grand Rapids Area Medical Education Center Visiting Professor: CephalosporinsTheir Selection and Use in Clinical Surgery. Grand Rapids, Michigan, November 1415, 1984.
  6. Baylor College of Medicine. Houston, Texas, November 29, 1984.
  7. University of Iowa College of Medicine. Iowa City, Iowa, December 8, 1984.
  8. Fourth Springfield Clinical Medical Symposium: The Fourth James Graham, M.D., Professorial Lectureship. Springfield, Illinois, May 1516, 1987.
  9. State University of New York at Buffalo. Buffalo, New York, August 19, 1989.
  10. Wilford Hall Medical Center and University of Texas School of Medicine Visiting Professor, Ft. Sam Houston, Texas, February 22-23, 1991.
  11. University of Minnesota. Minneapolis, Minnesota, March 27, 1991.
  12. University of Iowa, Cedar Rapids, Iowa, April 13, 1991.
  13. Millard Fillmore. Buffalo, New York, April 19, 1991.
  14. Providence Medical Center and Harborview Medical Center, Seattle, Washington, May 1, 1991.
  15. Dartmouth Medical College, Curts Visiting Professor. Hanover, New Hampshire, June 1, 1991.
  16. University of Medicine and Denistry of New Jersey, New Jersey Medical School. Newark, New Jersey, November 14, 1991.
  17. Mercy Hospital Trauma Center. Pittsburgh, Pennsylvania, December 7, 1991.
  18. Johns Hopkins Critical Care Program. Baltimore, Maryland. November 18, 1992.
  19. Spartanburg Regional Medical Center Surgical. December 1, 1992, Spartanburg, South Carolina.
  20. Ohio State University Critical Care Program. Columbus, Ohio, November 17-18, 1993.
  21. St. Francis Medical Center. Pittsburgh, Pennsylvania, March 89, 1994.
  22. Wright State University. Dayton, Ohio, April 6, 1994.
  23. The University of Mississippi Medical Center. Jackson, Mississippi, May 5, 1994.
  24. Kansas City Research Medical Center. Kansas City, Missouri, May 23-24, 1994.
  25. Medical College of Wisconsin. Milwaukee, Wisconsin, October 25, 1994.
  26. SUNY Health Science Center Visiting Professor. Brooklyn Surgical Society Lectureship and Triboro Association Surgical Grand Rounds. Brooklyn, New York, March 2-4, 1995.
  27. Albany Medical College. Albany, New York, Aug 13-14, 1996.

 

Stopped recording after 1997 (loss of vanity)

International

  1. International Congress on Intraabdominal Infections, Organizer, Hamburg, Germany, June 1-3, 1987.
  2. 4th European Congress of Clinical Microbiology. Monotherapy vs. combination therapies. Nice, France, April 17-20, 1989.
  3. Japanese Society for Emergency Surgery, Tokyo, Japan, March 7-9, 1990.
  4. Hospital General Gregorio Maranon, Visiting Professor. Madrid, Spain, March 30-31, 1992.
  5. International Congress of Surgery. Vigo, Spain, April 1-3, 1992.
  6. 4th Biennial Conference on Chemotherapy of Infectious Diseases and Malignancies. Clinical Studies in Prophylaxis and Treatment of Intra-Abdominal Infections: Use of Severity Scoring in Infection and Sepsis Trial. Prague, Czechoslovakia, August 30-September 1, 1992.
  7. Roussel Scientific Institute of Spain. Anti-inflammatory therapy in sepsis: evaluation through clinical trials. Madrid, Spain, October 30, 1992.
  8. Philippine College of Surgeons. Manila, the Philippines, December 5-9, 1992.
  9. Clinical evaluation of tienam in surgery: experience in U.S. Seoul, Korea, December 11, 1992.
  10. Symposium on surgical infections. Clinical trials in sepsis with biological response modifiers: requirements and pitfalls. Round Table: Biological approaches to sepsis. I. General strategies to down-regulate the inflammatory response. September 16, 1993, Madrid, Spain.
  11. 3rd International Congress on The Immune Consequences of Trauma, Shock and Sepsis. Analysis of membrane bound PMN. Utility of severity scoring systems in determining outcome from infection. Treatment of multiresistent gram-positive and gram-negative organisms. The crucial cellular element for the initiation of MODS/MOF. Azole drugs. Munich, Germany, March 25, 1994.
  12. Design of clinical anti-infective and sepsis therapy trials. Lessons learned from an antibiotic trial for nosocomial pneumonia. Paris, France, May 16-21, 1994.
  13. 7th European Congress of Clinical Microbiology and Infectious Diseases. Results of a trial of IV + PO Ciprofloxacin/Metronidazole vs Imipenem for complicated intra-abdominal infections. Vienna/Austria, March 26-30, 1995.
  14. 2nd International Conference on Sepsis in the ICU. Results of a trial of IV + PO Ciprofloxacin/Metronidazole (CIP/MTZ) vs Imipenem (IMI) for complicated intraabdominal infections. Maastricht, The Netherlands, June 27-29, 1995.
  15. Japanese Association for Emergency Medicine and Critical Care. Yokohama, Japan. October 9, 1996.
  16. Symposium on surgical infections. The clinical and laboratory findings in ARDS. Madrid, Spain, October 22, 1996.

Stopped recording after 1996 (loss of vanity)

Member, Special Site Visit Scientific Review Group, National Institutes of Health Burn and Trauma Center and Training Grants, 1987 to present

Consultant, Food and Drug Administration, Washington, DC, 1992-present

 

EDITORIAL BOARDS:

Surgical Infections:  Index & Reviews, 1993 to 1995; Senior Editor 1995 to present

Society of Critical Care Medicine (New Horizons) Editorial Board, 1993 to present

Shock, 2001 to present

 

REVIEWER:

American Journal of Physiology, Annals of Internal Medicine, Annals of Surgery, Archives of Surgery, American Journal of Infection Control, American Journal of Surgery, Antimicrobial Agents and Chemotherapy, British Journal of Surgery, Chest, Clinical Infectious Diseases, Critical Care, Critical Care Medicine, Drugs, European Journal of Clinical Microbiology and Infectious Diseases, Expert Reviews, Hospital Practice, Infection Control and Hospital Epidemiology, International Journal of Infectious Diseases, Intensive Care Medicine, Jounal of Leukocyte Biology, Journal of American Medical Association, British Journal of Surgery,Critical Care Medicine, Journal of Infectious Diseases, New England Journal of Medicine, Infection, Journal of Antimicrobial Therapy, Journal of the American College of Surgeons, Journal of Pediatric Surgery, Journal of Surgical Research, Medical Letter, New England Journal of Medicine, Scandinavian Journal of Infectious Diseases, Shock, Surgery

 

 

UNIVERSITY COMMITTEE APPOINTMENTS:

Member, Anti-infective Utilization Review Committee 1984-1987, 1991-present

Chairman 1984-1987, 1991-97, 2011-

Member, Pharmacy & Therapeutics Committee 1991-present

Member, Institutional Review Board 9/81-9/83; 9/90-94

Member, Infection Control Committee 9/81-present

Member, All University Faculty Senate 9/95-8/99

Member, Surgical Site Infection Prevention Committee 3/2009-present